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Madras et al (2006) inside a the latest paper shown in vivo binding of modafinil to striatal DAT and thalamic Web in rhesus monkeys using PET imaging. The investigators in comparison binding of the DAT probe [11C]CFT as well as the Internet probe [11C]MeNER during the absence of modafinil While using the binding of such probes in the presence of mo

In people who are deficient in CYP2D6, coadministration of modafinil with substrates of CYP2D6 that have ancillary routes of elimination by means of CYP2C19 (eg, tricyclic antidepressants and selective serotonin reuptake inhibitors) may well bring on elevated circulating amounts of these medicine and involve dose adjustment (Robertson et al 2000; P

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